History
This is a 46 year old man with a long standing history of chronic joint pain. He presents with a subcutaneous nodule over the left elbow.
Microscopic Findings
Sections show palisading granulomas surrounding an amorphous eosinophilic to amphophilic staining debris. | ||||
Figure 1 |
Higher power reveals a fine crystals present within the eosinophilic center surrounded by epithelioid histiocytes and rare giant cells. | ||||
Figure 2 |
In other sections of the same biopsy, palisading necrobiotic granulomas are noted. | ||||
Figure 3 |
On higher power, the eosinophilic center reveals areas of necrobiosis with rare nuclear dust and no evidence of crystals. No atypia of the epithelioid histiocytes is noted. |
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Figure 4 |
What is your diagnosis?
Last Updated 1/21/2003
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