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Case Posted 11.6.2002
Diagnosis
Cystic (Inverted) Warty Dyskeratoma
Discussion
Warty dyskeratomas are relatively common epithelial lesions characterized by invaginated cup-shaped cyst with an extensive keratotic and parakeratotic plug. Characteristically there is suprabasilar acantholysis with papillary fronds and numerous acantholytic cells with dyskeratosis forming corp ronds and corp grains. This recent paper cited below describes several histological variants including tumors which may exhibit follicular differentiation. PCR analysis for HPV DNA was negative in all cases, distinguishing it from verruca vulgaris and cystic verruca.
References
Warty Dyskeratoma and other Acanthomas
Kaddu S, Dong H, Mayer G, Kerl H, Cerroni L. Warty dyskeratoma--"follicular
dyskeratoma": analysis of clinicopathologic features of a distinctive follicular
adnexal neoplasm. J Am Acad Dermatol 2002 Sep;47(3):423-8
Last Updated 11/6/2002
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