Background

This rare tumor of the salivary glands is in the differential diagnosis of clear cell tumors of the salivary glands. It is a recently described tumor

Outline

Epidemiology
Gross Appearance and Clinical Variants
Histopathological Features and Variants
Special Stains/Immunohistochemistry/Electron Microscopy
Differential Diagnosis
Prognosis and Treatment
Commonly Used Terms
Internet Links

EPIDEMIOLOGY	CHARACTERIZATION
INCIDENCE	<20 cases reported
SEX (M:F)	Female predilection

 

GROSS APPEARANCE/ CLINICAL VARIANTS	CHARACTERIZATION
GENERAL	Intraoral minor salivary glands mainly in the base of the tounge and palate
VARIANTS

 

HISTOLOGICAL TYPES	CHARACTERIZATION
GENERAL	Am J Surg Pathol 19945;181:74-82 Solid masses, nests, infiltrating cords and single file cells with glycogen rich clear cells and smaller cells with eosinophilic cytoplasm Mitoses are rare Variable stromal hyalinization
VARIANTS

 

SPECIAL STAINS/IMMUNOPEROXIDASE/ OTHER	CHARACTERIZATION
SPECIAL STAINS	PAS positive diastase sensitive
IMMUNOPEROXIDASE

 

DIFFERENTIAL DIAGNOSIS	KEY DIFFERENTIATING FEATURES
Clear cell tumors of the salivary glands

 

PROGNOSIS AND TREATMENT	CHARACTERIZATION
PROGNOSTIC FACTORS	Relatively short follow-up with less than 10 years but no patients have died from the disease Recurrence rate of 8% 15% rate of metastasis to regional lymph nodes
TREATMENT	Excision

Rosai J. Ackerman's Surgical Pathology. Eight Edition. Mosby 1996.
Sternberg S. Diagnostic Surgical Pathology. Third Edition. Lipincott Williams and Wilkins 1999.

Salivary Glands

Last Updated 12/4/2001