Background
Rhinosporidiosis presents as a slow-growing, tumorlike mass, arising in the nasal mucosa or ocular conjunctivae of humans and animals. The symptoms vary with the location of the masss but patients with nasal involvement often have unilateral nasal obstruction or bleeding due to polyp formation. The pathologist establishes the diagnosis by the characteristic microscopic appearance of the organism in tissue biopsies.
This rare infection has been shrouded in mystery for many years. It was once thought to be a rare bacterial infection, possibly related to a cyanobacterium. Now, there is compelling evidence that it is caused by a rare parasite of fish.
INCIDENCE Survey of schoolchildren from Pallam, India, found 11 cases in 781 children examined (prevalence 1.4%) GEOGRAPHYEurope, Africa, and Asia but is most common in the tropics, with the highest prevalence in southern India and Sri Lanka
EPIDEMIOLOGIC ASSOCIATIONS CHARACTERIZATION Water activities Infection secondary to swimming or bathing in freshwater ponds, lakes, or rivers
PATHOGENESIS CHARACTERIZATION Rhinosporidium seeberi is a Protoctistan Mesomycetozoa J Clin Microbiol 199;37:2750-2754
Emerg Infect Dis 2000;6:(3)Cyanobacterium Microsystis Previous contender for etiology
SPECIAL STAINS/IMMUNOPEROXIDASE/OTHER CHARACTERIZATION Special stains Visualized with fungal stains such as methenamine silver and Periodic acid-Schiff, as well as mucicarmine
PROGNOSIS AND TREATMENT CHARACTERIZATION Prognostic Factors Recurrence 10% after surgical excision Treatment Surgical removal
Antiobiotic therapy ineffectiveHenry JB. Clinical Diagnosis and Management by Laboratory Methods. Twentieth Edition. WB Saunders. 2001.
Last Updated 3/8/2001
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